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KMID : 0371319720140050039
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Journal of the Korean Surgical Society
1972 Volume.14 No. 5 p.39 ~ p.45
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Carcinoma of Esophagus Developing at the Site of Lye Stricture
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金昌權/Kim, Changkwon
劉旻哲/閔丙駿/趙範九/洪承祿/Yoo, Minchul/Min, Byungjoon/Cho, Bumku/Hong, Seungnok
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Abstract
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The incidence of carcinoma of the esophagus among patients with chronic esophageal stricture, due
to ingestion of lye, is significantly higher than in the general population. Recently, we have seen 3
cases of scuh esophageal carcinoma and this report is to call attention the the importance of suspecting
development of carcinoma at the site of lye stricture ealry enough to institute curative treatment.
(1) All 3 cases of esophageal carcinoma developing at the site of lye stircture have historic of lye
ingestion 12 yaers, 15 years and 33 years respectively. The youngest was the 18 year old boy who had
taken lye in mistake of milk at the age 3 and developed esophageal carcinoma at age 18.
(2) The prognosis of esophageal carcinoma that develops in a patient, with chronic stricture due to
lye, is much better than for esophageal carcinoma in general. The better prognosis is due to following
three factors:
First, luminal obstruction is more apt to occur before development of extrinsic spread and thereby
lead to a relatively early diagnosis and more favorable prognosis.
Second, the dense scar tissue that initially forms in lye stricture tends to prevent early invasion of
the neoplastic cells to adjacent mediasinal structures and the favorable prognosis due to surgical
excision.
Third, the last factor is the interval of time that elpases between the ingestion of lye and the occ
urence of the carcinoma. In cases of lye ingestion in early childhood, esophageal carcinoma is occuring
in a much younger group than esophageal carcinoma in general.
(3) Surgery is the perferred method of treatment for esophageal carcinoma that develops at the site
of lye stricture rather than irradiation and a one-stage operation of esophagectomy and primary esopf
agogastric anastomosis within thorax seems the most recommendable procedure.
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